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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
29.39
Human Site:
Y417
Identified Species:
46.19
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
Y417
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Chimpanzee
Pan troglodytes
XP_511869
806
91579
Y612
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
L373
C
L
L
A
K
L
F
L
D
H
K
T
L
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
Y419
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Rat
Rattus norvegicus
Q810T5
612
70496
Y418
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
Y417
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Frog
Xenopus laevis
NP_001079995
617
71123
Y423
D
G
K
K
N
K
I
Y
C
Q
N
L
C
L
L
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
F386
L
C
L
L
A
K
L
F
L
D
H
K
T
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
Y359
L
D
H
K
T
L
Y
Y
D
T
D
P
F
L
F
Honey Bee
Apis mellifera
XP_392324
916
101344
Y709
D
G
K
R
Y
K
Q
Y
C
Q
N
L
C
L
L
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
P276
T
L
Y
Y
D
T
D
P
F
L
F
Y
V
L
T
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
P322
S
L
P
K
H
D
S
P
L
T
A
N
R
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
K263
Q
N
L
C
Y
L
A
K
L
F
L
D
H
K
T
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
T263
K
L
F
L
D
H
K
T
L
Y
Y
D
V
D
P
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
Y324
L
D
H
K
T
L
Y
Y
D
V
D
P
F
L
F
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
100
100
13.3
N.A.
20
80
6.6
6.6
P-Site Similarity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
100
100
33.3
N.A.
26.6
86.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
0
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
7
0
0
0
7
0
0
0
0
% A
% Cys:
7
7
0
7
0
0
0
0
47
0
0
0
47
0
0
% C
% Asp:
47
14
0
0
14
7
7
0
20
7
14
14
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
7
0
0
0
7
7
7
7
7
0
14
0
14
% F
% Gly:
0
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
14
0
7
7
0
0
0
7
7
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
47
60
7
54
7
7
0
0
7
7
0
7
7
% K
% Leu:
20
27
20
14
0
27
7
7
27
7
7
47
7
74
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
40
0
0
0
0
0
47
7
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
14
0
0
0
14
0
0
7
% P
% Gln:
7
0
0
0
0
0
7
0
0
47
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
14
7
0
7
0
14
0
7
7
0
14
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
14
0
14
60
0
7
7
7
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _